+ |
NEK3 | up-regulates activity
phosphorylation
|
SNAP29 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-273708 |
Ser105 |
MDQDLKIsQKHINSI |
Homo sapiens |
HEK-293 Cell |
pmid |
sentence |
29454964 |
In the present study, we show that NEK3 (NIMA-never in mitosis gene A-related kinase 3)-mediated serine 105 (S105) phosphorylation of SNAP29 directs its membrane association, without which cells present defective focal adhesion formation, impaired Golgi structure and attenuated cellular recycling. Our results highlight the importance of NEK3-mediated S105 phosphorylation of SNAP29 for its membrane localization and for membrane fusion dependent processes. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
NEK3 | down-regulates activity
phosphorylation
|
NEK3 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-260919 |
Thr165 |
FACTYVGtPYYVPPE |
in vitro |
|
pmid |
sentence |
27489110 |
Autophosphorylation at Thr-165 is required for NEK3 kinase activity in vitro. |
|
Publications: |
1 |
Organism: |
In Vitro |