Name
|
SLC25A1
|
Full Name |
Tricarboxylate transport protein, mitochondrial |
Synonyms |
Citrate transport protein, CTP, Solute carrier family 25 member 1, Tricarboxylate carrier protein | SLC20A3 |
Primary ID |
P53007 |
Links |
- - |
Type |
protein |
Relations |
2 |
Pathways |
Fatty Acid Synthesis, Glycolysis and Gluconeogenesis |
Function |
Citrate transporter that mediates the exchange of mitochondrial citrate for cytosolic malate (PubMed:29031613, PubMed:29238895). Also able to mediate the exchange of citrate for isocitrate, phosphoenolpyruvate, cis- but not trans-aconitate and to a lesser extend maleate and succinate (PubMed:29031613). Important for the bioenergetics of hepatic cells as it provides a carbon source for fatty acid and sterol biosyntheses, and NAD(+) for the glycolytic pathway. Required for proper neuromuscular junction formation (Probable). |