Summary

Name NUBP1
Full Name Cytosolic Fe-S cluster assembly factor NUBP1
Synonyms Nucleotide-binding protein 1, NBP 1 | NBP, NBP1
Primary ID P53384
Links - -
Type protein
Relations 1
Function Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery (PubMed:18573874). Required for maturation of extramitochondrial Fe-S proteins (PubMed:18573874). The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins (PubMed:18573874). Implicated in the regulation of centrosome duplication (By similarity). Negatively regulates cilium formation and structure (By similarity).

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Relations

Regulator Mechanism target score
+ form complex img/form-complex.png binding NUBP1-NUBP2 iron-sulfur cluster assembly scaffold complex 0.599
Publications: 1