3.0
Summary
| Name |  TMBIM6
|
| Full Name | Bax inhibitor 1 |
| Synonyms | BI-1, Testis-enhanced gene transcript protein, Transmembrane BAX inhibitor motif-containing protein 6 | BI1, TEGT |
| Primary ID | P55061 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Suppressor of apoptosis (PubMed:21075086). Modulates unfolded protein response signaling (PubMed:21075086). Modulates ER calcium homeostasis by acting as a calcium-leak channel (PubMed:22128171). Negatively regulates autophagy and autophagosome formation, especially during periods of nutrient deprivation, and reduces cell survival during starvation (By similarity). {ECO:0000250|UniProtKB:Q9D2C7, ECO:0000269|PubMed:21075086, ECO:0000269|PubMed:22128171}. |
polyubiquitination