Summary

Name MTTP
Full Name Microsomal triglyceride transfer protein large subunit
Synonyms MTP_HUMAN | MTP
Primary ID P55157
Links - -
Type protein
Relations 2
Function Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces (PubMed:23475612, PubMed:8939939, PubMed:26224785, PubMed:25108285, PubMed:22236406, PubMed:16478722, PubMed:15897609, PubMed:8876250). Required for the assembly and secretion of plasma lipoproteins that contain apolipoprotein B (PubMed:23475612, PubMed:8939939, PubMed:26224785, PubMed:8876250, PubMed:16478722). May be involved in regulating cholesteryl ester biosynthesis in cells that produce lipoproteins (By similarity).

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png lipidation APOB 0.786
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation MTTP 0.425
Publications: 1 Organism: Homo Sapiens