Relation Results

Summary

Name GFRA1
Full Name GDNF family receptor alpha-1
Synonyms GDNF receptor alpha-1, GDNFR-alpha-1, GFR-alpha-1, RET ligand 1, TGF-beta-related neurotrophic factor receptor 1 | GDNFRA, RETL1, TRNR1
Primary ID P56159
Links - -
Type protein
Relations 3
Function Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor (By similarity).

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Type: Score: Layout: SPV 
0.7490.7320.796RETGFRA1NRTNGDNF

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Relations
Regulator
Mechanism
target
score ℹ
+ RETup-regulates img/direct-activation.png binding GFRA1 0.749
Identifier Residue Sequence Organism Cell Line
SIGNOR-77587 Homo sapiens
pmid sentence
Gdnfr-alpha-ligand complex, together with the tyrosine kinase receptor (cret) forms a functional receptor that activates downstream signal transduction pathways
Publications: 1 Organism: Homo Sapiens
+ NRTNup-regulates img/direct-activation.png binding GFRA1 0.732
Identifier Residue Sequence Organism Cell Line
SIGNOR-49119 Homo sapiens Neuron
pmid sentence
A receptor complex comprised of trnr1 (gdnfr alpha) and ret was recently identified and found to be capable of mediating both gdnf and ntn signaling
Publications: 1 Organism: Homo Sapiens
Tissue: Brain
+ GDNFup-regulates img/direct-activation.png binding GFRA1 0.796
Identifier Residue Sequence Organism Cell Line
SIGNOR-49091 Homo sapiens Neuron
pmid sentence
A receptor complex comprised of trnr1 (gdnfr alpha) and ret was recently identified and found to be capable of mediating both gdnf and ntn signaling
Publications: 1 Organism: Homo Sapiens
Tissue: Brain
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