Summary

Name AP3S2
Full Name AP-3 complex subunit sigma-2
Synonyms AP-3 complex subunit sigma-3B, Adaptor-related protein complex 3 subunit sigma-2, Sigma-3B-adaptin, Sigma3B-adaptin, Sigma-adaptin 3b |
Primary ID P59780
Links - -
Type protein
Relations 1
Function Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

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Relations

Regulator Mechanism target score ℹ
+ AP3S2form complex img/form-complex.png binding Neuronal AP-3 0.699
Publications: 1 Organism: Homo Sapiens