Summary

Name SPCS3
Full Name Signal peptidase complex subunit 3
Synonyms Microsomal signal peptidase 22/23 kDa subunit, SPC22/23, SPase 22/23 kDa subunit | SPC22
Primary ID P61009
Links - -
Type protein
Relations 2
Function Essential component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (PubMed:27499293, PubMed:34388369). Essential for the SPC catalytic activity, possibly by stabilizing and positioning the active center of the complex close to the lumenal surface (By similarity).

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Relations

Regulator Mechanism target score ℹ
+ SPCS3form complex img/form-complex.png binding Signal peptidase complex, SEC11C variant 0.735
Publications: 1 Organism: Homo Sapiens
+ SPCS3form complex img/form-complex.png binding Signal peptidase complex, SEC11A variant 0.716
Publications: 1 Organism: Homo Sapiens