| + |
MDM2 | down-regulates quantity by destabilization 
ubiquitination
|
RPL26 |
0.507 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-278828 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 18951086 |
In addition, Mdm2 ubiquitylates L26, leading to its proteasome-mediated degradation.|We now report that Mdm2 regulates p53 levels also by targeting ribosomal protein L26. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RPL26 | form complex 
binding
|
60S cytosolic large ribosomal subunit |
0.859 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-262497 |
|
|
in vitro |
|
| pmid |
sentence |
| 25901680 |
Here we report the near-atomic structure of the human ribosome derived from high-resolution single-particle cryo-electron microscopy and atomic model building. The structure has an average resolution of 3.6 Å, reaching 2.9 Å resolution in the most stable regions. |The human ribosome (80S) has a molecular weight of 4.3 MDa: the large subunit (60S) consists of 28S, 5S and 5.8S rRNAs and 47 proteins, while the small subunit (40S) possesses a single 18S rRNA chain and 33 pro- teins. |
|
| Publications: |
1 |
Organism: |
In Vitro |
3.0
RPL26
- 
- 