Summary

Name SNRPD1
Full Name Small nuclear ribonucleoprotein Sm D1
Synonyms Sm-D1, Sm-D autoantigen, snRNP core protein D1 |
Primary ID P62314
Links - -
Type protein
Relations 3
Function Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:11991638, PubMed:18984161, PubMed:19325628, PubMed:23333303, PubMed:25555158, PubMed:26912367, PubMed:28502770, PubMed:28781166, PubMed:28076346). Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (PubMed:11991638, PubMed:26912367, PubMed:28502770, PubMed:28781166, PubMed:28076346). Is also a component of the minor U12 spliceosome (PubMed:15146077). May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA (Probable).

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Relations

Regulator Mechanism target score
+ form complex img/form-complex.png binding U2 snRNP complex 0.734
Publications: 1 Organism: Homo Sapiens
+ form complex img/form-complex.png binding U1 snRNP complex 0.905
Publications: 1 Organism: Homo Sapiens
+ form complex img/form-complex.png binding U4/U6.U5 snRNP complex 0.813
Publications: 1 Organism: Homo Sapiens