Summary

Name H2BC4
Full Name Histone H2B type 1-C/E/F/G/I
Synonyms Histone H2B.1 A, Histone H2B.a, H2B/a, Histone H2B.g, H2B/g, Histone H2B.h, H2B/h, Histone H2B.k, H2B/k, Histone H2B.l, H2B/l | H2BFL, HIST1H2BE, HIST1H2BF, HIST1H2BG, HIST1H2BI, HIST1H2BE, HIST1H2BF, HIST1H2BG, HIST1H2BI, HIST1H2BE, HIST1H2BF, HIST1H2BG, HIST1H2BI, HIST1H2BE, HIST1H2BF, HIST1H2BG, HIST1H2BI, H2BC6, H2BC7, H2BC8, H2BC10, H2BC6, H2BC7, H2BC8, H2BC10, H2BC6, H2BC7, H2BC8, H2BC10
Primary ID P62807
Links - -
Type protein
Relations 2
Function Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.; FUNCTION

Viewer

Modifications Tables

Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png monoubiquitination H2BC4 0.2
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/direct-activation.png translation regulation H2BC4 0.2
Publications: 1 Organism: Homo Sapiens