| + |
SMO | up-regulates
binding
|
GNB2 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-148589 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 16885213 |
Consistent with its predicted topology, smo couples to a specific family of inhibitory g protein (gis) to regulate hh signaling. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-199177 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 23074268 |
Consistent with its predicted topology, smo couples to a specific family of inhibitory g protein (gis) to regulate hh signaling. |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| + |
GNB2 | up-regulates
|
PLCG1 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-199132 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 23074268 |
Furthermore, this work suggested that the gbetagamma subunits released upon gi activation activated phospholipase c-gamma (plc-gamma) to produce inositol 3 phosphate (ip3) which would subsequently increase intracellular ca2+ abundance. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |