| Name
|
 TRA2B
|
| Full Name |
Transformer-2 protein homolog beta |
| Synonyms |
TRA-2 beta, TRA2-beta, hTRA2-beta, Splicing factor, arginine/serine-rich 10, Transformer-2 protein homolog B | SFRS10 |
| Primary ID |
P62995 |
| Links |
 -  -  |
| Type |
protein |
| Relations |
2 |
| Function |
Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor neuron SMN2. Activates the splicing of MAPT/Tau exon 10. Alters pre-mRNA splicing patterns by antagonizing the effects of splicing regulators, like RBMX. Binds to the AG-rich SE2 domain in the SMN exon 7 RNA. Binds to pre-mRNA. |
3.0
transcriptional regulation