+ |
SYK | up-regulates activity
phosphorylation
|
SH3BP2 |
0.567 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-246587 |
Tyr174 |
YPTDNEDyEHDDEDD |
Chlorocebus aethiops |
|
pmid |
sentence |
12709437 |
By using the transient expression system in COS-7 cells, we have demonstrated that 3BP2 was predominantly phosphorylated on Tyr174, Tyr183, and Tyr446 when it was coexpressed with Syk. |
|
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-246592 |
Tyr183 |
HDDEDDSyLEPDSPE |
Chlorocebus aethiops |
COS Cell |
pmid |
sentence |
12709437 |
By using the transient expression system in COS-7 cells, we have demonstrated that 3BP2 was predominantly phosphorylated on Tyr174, Tyr183, and Tyr446 when it was coexpressed with Syk |
|
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-246596 |
Tyr448 |
GDDSDEDyEKVPLPN |
Chlorocebus aethiops |
COS Cell |
pmid |
sentence |
12709437 |
By using the transient expression system in COS-7 cells, we have demonstrated that 3BP2 was predominantly phosphorylated on Tyr174, Tyr183, and Tyr446 when it was coexpressed with Syk. |
|
Publications: |
3 |
Organism: |
Chlorocebus Aethiops |
+ |
PTPN6 | down-regulates activity
dephosphorylation
|
SH3BP2 |
0.553 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-277172 |
Tyr448 |
GDDSDEDyEKVPLPN |
Homo sapiens |
|
pmid |
sentence |
16649996 |
Shp-1 dephosphorylates 3bp2 and potentially downregulates 3bp2-mediated t cell antigen receptor signaling|adaptor protein 3BP2 serves as a binding protein and a physiological substrate of SHP-1. 3BP2 is phosphorylated on tyrosyl residue 448 in response to TCR activation, and the phosphorylation is required for T c |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
PTPN6 | down-regulates
dephosphorylation
|
SH3BP2 |
0.553 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-146508 |
|
|
Homo sapiens |
|
pmid |
sentence |
16649996 |
Shp-1 dephosphorylates 3bp2 and potentially downregulates 3bp2-mediated t cell antigen receptor signaling |
|
Publications: |
1 |
Organism: |
Homo Sapiens |