4.0
Summary
| Name |  PRAME
|
| Full Name | Melanoma antigen preferentially expressed in tumors |
| Synonyms | Opa-interacting protein 4, OIP-4, Preferentially expressed antigen of melanoma | MAPE, OIP4 |
| Primary ID | P78395 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis. |
transcriptional regulation