| Name
|
 IRX3
|
| Full Name |
Iroquois-class homeodomain protein IRX-3 |
| Synonyms |
Homeodomain protein IRXB1, Iroquois homeobox protein 3 | IRXB1 |
| Primary ID |
P78415 |
| Links |
 -  -  |
| Type |
protein |
| Relations |
1 |
| Function |
Transcription factor involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells. Acts as a regulator of energy metabolism. |
4.0
transcriptional regulation