3.0
Summary
| Name |  XPCView Modifications |
| Full Name | DNA repair protein complementing XP-C cells |
| Synonyms | Xeroderma pigmentosum group C-complementing protein, p125 | XPCC |
| Primary ID | Q01831 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex (PubMed:10734143, PubMed:19609301, PubMed:20649465, PubMed:9734359, PubMed:10873465, PubMed:12509299, PubMed:12547395, PubMed:19941824, PubMed:20028083, PubMed:20798892). Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides (PubMed:10734143, PubMed:19609301, PubMed:20649465). This feature is proposed to be related to a dynamic sensor function |
Viewer
Search Tools
Refine search:
- by mechanism
- by effect
- by organism:
- by tissue:
- by cell-line
phosphorylation