3.0
Summary
| Name |  MLLT1
|
| Full Name | Protein ENL |
| Synonyms | YEATS domain-containing protein 1 | ENL, LTG19, YEATS1 |
| Primary ID | Q03111 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Chromatin reader component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA (PubMed:20159561, PubMed:20471948). Specifically recognizes and binds acetylated and crotonylated histones, with a preference for histones that are crotonylated (PubMed:27105114). Has a slightly higher affinity for binding histone H3 crotonylated at 'Lys-27' (H3K27cr) than 'Lys-20' (H3K9cr20) (PubMed:27105114). |
Viewer
Search Tools
Refine search:
- by mechanism
- by effect
- by organism:
- by tissue:
- by cell-line
phosphorylation
binding