+ |
YWHAH | down-regulates
binding
|
CDKN1B |
0.479 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-109771 |
|
|
Homo sapiens |
|
pmid |
sentence |
12042314 |
14-3-3_, 14-3-3_, and 14-3-3_ (but not 14-3-3_ and 14-3-3_) could form a complex with p27kip1 / we discovered that akt-mediated p27kip1phosphorylation directly induces p27kip1binding to 14-3-3 and cytoplasmic localization through phosphorylating the newly identified thr198residue. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
YWHAH | down-regulates activity
binding
|
KCNK18 |
0.314 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-263155 |
|
|
in vitro |
|
pmid |
sentence |
18397886 |
Phosphorylation of serine 264 in mouse TRESK was required for the binding of 14-3-3η. In the present study, we report that 14-3-3 proteins directly bind to the intracellular loop of TRESK and control the kinetics of the calcium-dependent regulation of the channel. Coexpression of 14-3-3η with TRESK blocked, whereas the coexpression of a dominant negative form of 14-3-3η accelerated the return of the K+ current to the resting state after the activation mediated by calcineurin in Xenopus oocytes. |
|
Publications: |
1 |
Organism: |
In Vitro |