Relation Results

Summary

Name PSME1
Full Name Proteasome activator complex subunit 1
Synonyms 11S regulator complex subunit alpha, REG-alpha, Activator of multicatalytic protease subunit 1, Interferon gamma up-regulated I-5111 protein, IGUP I-5111, Proteasome activator 28 subunit alpha, PA28a, PA28alpha | IFI5111
Primary ID Q06323
Links - -
Type protein
Relations 1
Function Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I b ...
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Type: Score: Layout: SPV 
0.596PSME126S Proteasome

Relations

Regulator
Mechanism
target
score
+ up-regulates activity img/direct-activation.png binding 26S Proteasome 0.596
Identifier Residue Sequence Organism Cell Line
SIGNOR-275867
pmid sentence
While PA28alpha beta is responsible for promoting peptidase activity of proteasome to facilitate MHC-I antigen processing, but unable to promote protein degradation, PA28gamma is well-known to not only promote peptidase activity but also proteolytic activity of proteasome.
Publications: 1
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