Summary

Name SLC20A2
Full Name Sodium-dependent phosphate transporter 2
Synonyms Gibbon ape leukemia virus receptor 2, GLVR-2, Phosphate transporter 2, PiT-2, Pit2, hPit2, Solute carrier family 20 member 2 | GLVR2, PIT2
Primary ID Q08357
Links - -
Type protein
Relations 1
Function Sodium-phosphate symporter which seems to play a fundamental housekeeping role in phosphate transport by absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. In vitro, sodium-dependent phosphate uptake is not significantly affected by acidic and alkaline conditions, however sodium-independent phosphate uptake occurs at acidic conditions. May play a role in extracellular matrix, cartilage and vascular calcification. Functions as a retroviral receptor and confers human cells susceptibility to infection to amphotropic murine leukemia virus (A-MuLV), 10A1 murine leukemia virus (10A1 MLV) and some feline leukemia virus subgroup B (FeLV-B) variants.

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Relations

Regulator Mechanism target score
+ up-regulates quantity img/direct-activation.png relocalization phosphate(3-) 0.8
Publications: 1 Organism: Homo Sapiens