Summary

Name VAC14
Full Name Protein VAC14 homolog
Synonyms Tax1-binding protein 2 | TAX1BP2, TRX
Primary ID Q08AM6
Links - -
Type protein
Relations 3
Function The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Acts as a positive activator of PIKfyve kinase activity. Also required to maintain normal levels of phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 5-phosphate (PtdIns(5)P). Plays a role in the biogenesis of endosome carrier vesicles (ECV) / multivesicular bodies (MVB) transport intermediates from early endosomes.

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Relations

Regulator Mechanism target score
+ form complex img/form-complex.png binding PAS complex 0.923
Publications: 1 Organism: Homo Sapiens
+ img/unknown.png binding VAC14 0.305
Publications: 1 Organism: Mus Musculus
+ up-regulates quantity by stabilization img/direct-activation.png binding FIG4 0.919
Publications: 1 Organism: Chlorocebus Aethiops