Summary

Name CPSF1
Full Name Cleavage and polyadenylation specificity factor subunit 1
Synonyms Cleavage and polyadenylation specificity factor 160 kDa subunit, CPSF 160 kDa subunit | CPSF160
Primary ID Q10570
Links - -
Type protein
Relations 1
Function Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (PubMed:14749727). May play a role in eye morphogenesis and the development of retinal ganglion cell projections to the midbrain (By similarity).

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Relations

Regulator Mechanism target score
+ form complex img/form-complex.png binding CPSF complex 0.939
Publications: 1 Organism: Homo Sapiens