3.0
Summary
| Name |  CPSF1
|
| Full Name | Cleavage and polyadenylation specificity factor subunit 1 |
| Synonyms | Cleavage and polyadenylation specificity factor 160 kDa subunit, CPSF 160 kDa subunit | CPSF160 |
| Primary ID | Q10570 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (PubMed:14749727). May play a role in eye morphogenesis and the development of retinal ganglion cell projections to the midbrain (By similarity). |
Viewer
Search Tools
Refine search:
- by mechanism
- by effect
- by organism:
- by tissue:
- by cell-line
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | CPSF1 | form complex 
binding
|
CPSF complex | 0.939 |
| Publications: | 1 | Organism: | Homo Sapiens | |