Summary

Name FLII
Full Name Protein flightless-1 homolog
Synonyms FLII_HUMAN | FLIL
Primary ID Q13045
Links - -
Type protein
Relations 2
Function May play a role as coactivator in transcriptional activation by hormone-activated nuclear receptors (NR) and acts in cooperation with NCOA2 and CARM1. Involved in estrogen hormone signaling. Involved in early embryonic development (By similarity). May play a role in regulation of cytoskeletal rearrangements involved in cytokinesis and cell migration, by inhibiting Rac1-dependent paxillin phosphorylation.

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png phosphorylation FLII 0.364
Publications: 2 Organism: Homo Sapiens