Summary

Name TCOF1
Full Name Treacle protein
Synonyms Treacher Collins syndrome protein |
Primary ID Q13428
Links - -
Type protein
Relations 2
Function Nucleolar protein that acts as a regulator of RNA polymerase I by connecting RNA polymerase I with enzymes responsible for ribosomal processing and modification (PubMed:12777385, PubMed:26399832). Required for neural crest specification

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png phosphorylation TCOF1 0.309
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png relocalization NBN 0.324
Publications: 1 Organism: Homo Sapiens