Summary

Name IL18R1
Full Name Interleukin-18 receptor 1
Synonyms IL-18R-1, IL-18R1, CD218 antigen-like family member A, CDw218a, IL1 receptor-related protein, IL-1Rrp, IL1R-rp | IL1RRP
Primary ID Q13478
Links - -
Type protein
Relations 1
Function Within the IL18 receptor complex, responsible for the binding of the proinflammatory cytokine IL18, but not IL1A nor IL1B (PubMed:8626725, PubMed:14528293, PubMed:25261253, PubMed:25500532). Involved in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (PubMed:10653850). Contributes to IL18-induced cytokine production, either independently of SLC12A3, or as a complex with SLC12A3 (By similarity).

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png binding IL18R1 0.831
Publications: 1 Organism: Homo Sapiens