Summary

Name MTMR1
Full Name Myotubularin-related protein 1
Synonyms Phosphatidylinositol-3,5-bisphosphate 3-phosphatase, 3.1.3.95, Phosphatidylinositol-3-phosphate phosphatase, 3.1.3.64 |
Primary ID Q13613
Links - -
Type protein
Relations 2
Function Lipid phosphatase that has high specificity for phosphatidylinositol 3-phosphate and has no activity with phosphatidylinositol 4-phosphate, phosphatidylinositol (4,5)-bisphosphate and phosphatidylinositol (3,4,5)-trisphosphate (PubMed:11733541, PubMed:27018598). Activity with phosphatidylinositol (3,5)-bisphosphate is controversial; it has been shown by PubMed:27018598, while PubMed:11733541 find no activity with this substrate.

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Relations

Regulator Mechanism target score
+ down-regulates quantity img/direct_inhibition.png chemical modification 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate(5-) 0.8
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity img/direct-activation.png chemical modification 1-phosphatidyl-1D-myo-inositol 5-phosphate(3-) 0.8
Publications: 1 Organism: Homo Sapiens