4.0
Summary
| Name |  MTMR1
|
| Full Name | Myotubularin-related protein 1 |
| Synonyms | Phosphatidylinositol-3,5-bisphosphate 3-phosphatase, 3.1.3.95, Phosphatidylinositol-3-phosphate phosphatase, 3.1.3.64 | |
| Primary ID | Q13613 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Lipid phosphatase that has high specificity for phosphatidylinositol 3-phosphate and has no activity with phosphatidylinositol 4-phosphate, phosphatidylinositol (4,5)-bisphosphate and phosphatidylinositol (3,4,5)-trisphosphate (PubMed:11733541, PubMed:27018598). Activity with phosphatidylinositol (3,5)-bisphosphate is controversial; it has been shown by PubMed:27018598, while PubMed:11733541 find no activity with this substrate. |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | MTMR1 | down-regulates quantity 
chemical modification
|
1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate(5-) | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | MTMR1 | up-regulates quantity 
chemical modification
|
1-phosphatidyl-1D-myo-inositol 5-phosphate(3-) | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |