Summary

Name SEPTIN6
Full Name Septin-6
Synonyms SEPT6_HUMAN | KIAA0128, SEP2
Primary ID Q14141
Links - -
Type protein
Relations 3
Function Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Involved in cytokinesis. May play a role in HCV RNA replication. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (PubMed:25588830).

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Relations

Regulator Mechanism target score ℹ
+ SEPTIN12down-regulates img/direct_inhibition.png binding SEPTIN6 0.2
Publications: 1 Organism: Homo Sapiens
+ SEPTIN6form complex img/form-complex.png binding SEPT6/SEPT2 0.2
Publications: 1 Organism: Homo Sapiens
+ SEPTIN6form complex img/form-complex.png binding SEPT6/SEPT7 0.2
Publications: 1 Organism: Homo Sapiens