Summary

Name SEPTIN12
Full Name Septin-12
Synonyms SEP12_HUMAN
Primary ID Q8IYM1
Links - -
Type protein
Relations 1
Function Filament-forming cytoskeletal GTPase (By similarity). Involved in spermatogenesis. Involved in the morphogenesis of sperm heads and the elongation of sperm tails probably implicating the association with alpha- and beta-tubulins (PubMed:24213608). Forms a filamentous structure with SEPTIN7, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (PubMed:25588830). May play a role in cytokinesis (Potential).

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Relations

Regulator Mechanism target score ℹ
+ SEPTIN12down-regulates img/direct_inhibition.png binding SEPTIN6 0.2
Publications: 1 Organism: Homo Sapiens