Summary

Name NPAT
Full Name Protein NPAT
Synonyms Nuclear protein of the ataxia telangiectasia mutated locus, Nuclear protein of the ATM locus, p220 | CAND3, E14
Primary ID Q14207
Links - -
Type protein
Relations 2
Function Required for progression through the G1 and S phases of the cell cycle and for S phase entry. Activates transcription of the histone H2A, histone H2B, histone H3 and histone H4 genes in conjunction with MIZF. Also positively regulates the ATM, MIZF and PRKDC promoters. Transcriptional activation may be accomplished at least in part by the recruitment of the NuA4 histone acetyltransferase (HAT) complex to target gene promoters.

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png phosphorylation NPAT 0.461
Publications: 2 Organism: Homo Sapiens