Summary

Name E2F2
Full Name Transcription factor E2F2
Synonyms E2F-2
Primary ID Q14209
Links - -
Type protein
Relations 3
Function Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from g1 to s phase. E2F2 binds specifically to RB1 in a cell-cycle dependent manner.

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Relations

Regulator Mechanism target score
+ down-regulates img/direct_inhibition.png binding E2F2 0.91
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding TFDP1 0.724
Publications: 1 Organism: Cricetulus Griseus
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation CCNE1 0.59
Publications: 1 Organism: Homo Sapiens