Summary

Name ENDOG
Full Name Endonuclease G, mitochondrial
Synonyms Endo G
Primary ID Q14249
Links - -
Type protein
Relations 2
Function Cleaves DNA at double-stranded (DG)n.(DC)n and at single-stranded (DC)n tracts. In addition to deoxyribonuclease activities, also has ribonuclease (RNase) and RNase H activities. Capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA (By similarity).

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Relations

Regulator Mechanism target score
+ up-regulates img/indirect-activation.png ENDOG 0.297
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/indirect-activation.png BAX 0.358
Publications: 1 Organism: Homo Sapiens