+ |
INSR | up-regulates
binding
|
GRB7 |
0.43 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-77153 |
|
|
Homo sapiens |
|
pmid |
sentence |
10803466 |
Insulin induces the ir-grb7 interaction in cells expressing physiological levels of the proteins, suggesting that grb7 is implicated in insulin signaling. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
RET | up-regulates
binding
|
GRB7 |
0.547 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-41765 |
|
|
Homo sapiens |
|
pmid |
sentence |
8631863 |
Grb7 and grb10, likely relay signals emanating from ret to other, as yet, unidentified targets within the cell |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
GRB7 | up-regulates
binding
|
RND1 |
0.618 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-74914 |
|
|
Homo sapiens |
Breast Cancer Cell |
pmid |
sentence |
10664463 |
We would like to propose that when cells are driven to divide by growth factor stimulation, grb7 relocalizes at the membrane, in the same subcellular compartment as rnd1, where they could interact in vivo. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
KIT | up-regulates activity
binding
|
GRB7 |
0.561 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-248291 |
|
|
Homo sapiens |
HeLa Cell |
pmid |
sentence |
10377264 |
We furthermore demonstrate that the adapter protein Grb2 is a specific binding partner for both phosphorylated Tyr-703 and phosphorylated Tyr-936, whereas the adapter protein Grb7 binds selectively to phosphorylated Tyr-936. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |