| + |
DMC1 | up-regulates activity 
binding
|
SYCP3 |
0.389 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264206 |
|
|
Mus musculus |
Spermatocyte |
| pmid |
sentence |
| 10525529 |
The eukaryotic RecA homologues RAD51 and DMC1 function in homology recognition and formation of joint-molecule recombination intermediates during yeast meiosis. We also show that mouse RAD51 and DMC1 establish protein-protein interactions with each other and with the chromosome core component COR1(SCP3) in a two-hybrid system and in vitro binding analyses. These results suggest that the formation of a multiprotein recombination complex associated with the meiotic chromosome cores is essential for the development and fulfillment of the meiotic recombination process. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
HOP2-MND1 recombination assembly factor complex | up-regulates activity
binding
|
DMC1 |
0.65 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-281474 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 24943459 |
The HOP2-MND1 heterodimer is required for progression of homologous recombination in eukaryotes. In vitro, HOP2-MND1 stimulates the DNA strand exchange activities of RAD51 and DMC1. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
DMC1 | up-regulates activity
binding
|
Synaptonemal_complex |
0.34 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264208 |
|
|
Mus musculus |
Spermatocyte |
| pmid |
sentence |
| 10525529 |
The eukaryotic RecA homologues RAD51 and DMC1 function in homology recognition and formation of joint-molecule recombination intermediates during yeast meiosis. We also show that mouse RAD51 and DMC1 establish protein-protein interactions with each other and with the chromosome core component COR1(SCP3) in a two-hybrid system and in vitro binding analyses. These results suggest that the formation of a multiprotein recombination complex associated with the meiotic chromosome cores is essential for the development and fulfillment of the meiotic recombination process. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
4.0
DMC1
- 
- 