3.0
Summary
| Name |  ITPR2View Modifications |
| Full Name | Inositol 1,4,5-trisphosphate receptor type 2 |
| Synonyms | IP3 receptor isoform 2, IP3R 2, InsP3R2, Type 2 inositol 1,4,5-trisphosphate receptor, Type 2 InsP3 receptor | |
| Primary ID | Q14571 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. This release is regulated by cAMP both dependently and independently of PKA (By similarity). |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | CAMK2D | down-regulates activity 
phosphorylation
|
ITPR2 | 0.313 |
| Publications: | 1 | Organism: | Chlorocebus Aethiops | |
| + | Erlin | down-regulates quantity by destabilization
binding
|
ITPR2 | 0.357 |
| Publications: | 1 | Organism: | Rattus Fuscipes | |
| + | RNF170 | down-regulates activity
polyubiquitination
|
ITPR2 | 0.338 |
| Publications: | 1 | Organism: | Homo Sapiens | |