Relation Results

Summary

Name LBR
Full Name Delta
Synonyms Integral nuclear envelope inner membrane protein, LMN2R
Primary ID Q14739
Links - -
Type protein
Relations 1
Function Catalyzes the reduction of the C14-unsaturated bond of lanosterol, as part of the metabolic pathway leading to cholesterol biosynthesis (PubMed:963065 ...
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Type: Score: Layout: SPV 
0.403CDK1LBR

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▶Modifications Tables

Relations
Regulator
Mechanism
target
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+ CDK1down-regulates img/direct_inhibition.png phosphorylation LBR 0.403
Identifier Residue Sequence Organism Cell Line
SIGNOR-121335 Ser71 KGGSTSSsPSRRRGS Homo sapiens
pmid sentence
The binding of the nk fragment to chromatin pretreated with an s-phase extract was suppressed by incubation with an m-phase extract. Enzyme inhibitor experiments revealed that multiple kinases participate in the suppression. One of these kinases was shown to be cdc2 experiments involving a mutant nk fragment showed that the phosphorylation of serine 71 by cdc2 kinase is responsible for the suppression.
Publications: 1 Organism: Homo Sapiens
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