+ |
CyclinB/CDK1 | up-regulates
phosphorylation
|
KIF22 |
0.374 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-216793 |
Thr463 |
QGAPLLStPKRERMV |
Homo sapiens |
|
pmid |
sentence |
12727876 |
Cdc2-mediated phosphorylation of kid controls its distribution to spindle and chromosomes. We identify ser427 and thr463 as m phase-specific phosphorylation sites and cdc2-cyclin b as a thr463 kinase. Kid with a thr463 to alanine mutation fails to be localized on chromosomes and is only detected along spindles, although it retains the ability to bind dna or chromosomes |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
CDK1 | up-regulates activity
phosphorylation
|
KIF22 |
0.35 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-100964 |
Thr463 |
QGAPLLStPKRERMV |
Homo sapiens |
|
pmid |
sentence |
12727876 |
Cdc2-mediated phosphorylation of kid controls its distribution to spindle and chromosomes. We identify ser427 and thr463 as m phase-specific phosphorylation sites and cdc2-cyclin b as a thr463 kinase. Kid with a thr463 to alanine mutation fails to be localized on chromosomes and is only detected along spindles, although it retains the ability to bind dna or chromosomes |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
CHFR | down-regulates quantity by destabilization
ubiquitination
|
KIF22 |
0.408 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-271469 |
|
|
Homo sapiens |
HeLa Cell |
pmid |
sentence |
19321445 |
Chfr ubiquitinates Kif22 and promotes its degradation. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |