Summary

Name NCAPH
Full Name Condensin complex subunit 2
Synonyms Barren homolog protein 1, Chromosome-associated protein H, hCAP-H, Non-SMC condensin I complex subunit H, XCAP-H homolog | BRRN, BRRN1, CAPH, KIAA0074
Primary ID Q15003
Links - -
Type protein
Relations 1
Function Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (PubMed:11136719). Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size (PubMed:27737959).

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Relations

Regulator Mechanism target score ℹ
+ NCAPHform complex img/form-complex.png binding Condensin I 0.968
Publications: 1 Organism: Homo Sapiens