Summary

Name SPCS2
Full Name Signal peptidase complex subunit 2
Synonyms Microsomal signal peptidase 25 kDa subunit, SPase 25 kDa subunit | KIAA0102, SPC25
Primary ID Q15005
Links - -
Type protein
Relations 2
Function Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (PubMed:34388369). Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site (By similarity).

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Relations

Regulator Mechanism target score ℹ
+ SPCS2form complex img/form-complex.png binding Signal peptidase complex, SEC11C variant 0.815
Publications: 1 Organism: Homo Sapiens
+ SPCS2form complex img/form-complex.png binding Signal peptidase complex, SEC11A variant 0.743
Publications: 1 Organism: Homo Sapiens