Summary

Name RAB3GAP1
Full Name Rab3 GTPase-activating protein catalytic subunit
Synonyms RAB3 GTPase-activating protein 130 kDa subunit, Rab3-GAP p130, Rab3-GAP | KIAA0066, RAB3GAP
Primary ID Q15042
Links - -
Type protein
Relations 2
Function Probable catalytic subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.

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Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png gtpase-activating protein RAB3A 0.453
Publications: 1 Organism: Rattus Norvegicus
Tissue: Brain
+ up-regulates quantity img/direct-activation.png binding RAB3GAP1 0.557
Publications: 1 Organism: Rattus Norvegicus
Tissue: Brain