+ |
RAB3GAP1 | down-regulates activity
gtpase-activating protein
|
RAB3A |
0.453 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-265580 |
|
|
Rattus norvegicus |
|
pmid |
sentence |
11809763 |
Rab3A, a member of the Rab3 small G protein family, regulates Ca(2+)-dependent exocytosis of neurotransmitter. The cyclical activation and inactivation of Rab3A are essential for the Rab3A action in exocytosis. GDP-Rab3A is activated to GTP-Rab3A by Rab3 GDP/GTP exchange protein (Rab3 GEP), and GTP-Rab3A is inactivated to GDP-Rab3A by Rab3 GTPase-activating protein (Rab3 GAP). |
|
Publications: |
1 |
Organism: |
Rattus Norvegicus |
Tissue: |
Brain |
+ |
DMXL2 | up-regulates quantity
binding
|
RAB3GAP1 |
0.557 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-265582 |
|
|
Rattus norvegicus |
|
pmid |
sentence |
11809763 |
We isolated here a novel protein that was co-immunoprecipitated with Rab3 GEP and GAP by their respective antibodies from the crude synaptic vesicle fraction of rat brain. The protein, named rabconnectin-3, bound both Rab3 GEP and GAP. These results indicate that rabconnectin-3 serves as a scaffold molecule for both Rab3 GEP and GAP on synaptic vesicles. |
|
Publications: |
1 |
Organism: |
Rattus Norvegicus |
Tissue: |
Brain |