4.0
Summary
| Name |  RABEP1View Modifications |
| Full Name | Rab GTPase-binding effector protein 1 |
| Synonyms | Rabaptin-4, Rabaptin-5, Rabaptin-5alpha, Renal carcinoma antigen NY-REN-17 | RAB5EP, RABPT5, RABPT5A |
| Primary ID | Q15276 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Involved in KCNH1 channels trafficking to and from the cell membrane (PubMed:22841712). Stimulates RABGEF1 mediated nucleotide exchange on RAB5A. Mediates the traffic of PKD1:PKD2 complex from the endoplasmic reticulum through the Golgi to the cilium (By similarity). |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | PRKD1 | up-regulates activity 
phosphorylation
|
RABEP1 | 0.383 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | RABEP1 | up-regulates
binding
|
RAB5A | 0.929 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | RABEP1 | up-regulates
binding
|
RABGEF1 | 0.942 |
| Publications: | 1 | Organism: | Homo Sapiens | |