| + |
AP-1/clathrin vescicle | up-regulates activity 
relocalization
|
RABGEF1 |
0.328 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-260706 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 27411398 |
AP-1/sigma1A-ArfGAP1-Rabex-5 complex formation leads to more endosomal Rabex-5 and enhanced, Rab5GTP-stimulated Vps34 PI3-kinase activity, which is essential for multivesicular body endosome formation. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
RABGEF1 | up-regulates activity
guanine nucleotide exchange factor
|
RAB5A |
0.921 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-260707 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 27411398 |
AP-1/sigma1A-ArfGAP1-Rabex-5 complex formation leads to more endosomal Rabex-5 and enhanced, Rab5GTP-stimulated Vps34 PI3-kinase activity, which is essential for multivesicular body endosome formation. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
RABEP1 | up-regulates
binding
|
RABGEF1 |
0.941 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-109395 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 11452015 |
We show that rabaptin-5 increases the exchange activity of rabex-5 on rab5. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RABGEF1 | up-regulates
binding
|
RAB5A |
0.921 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-109398 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 11452015 |
We have previously shown that rab5, which regulates various steps of transport along the early endocytic pathway, is activated by a complex consisting of rabex-5, a rab5 nucleotide exchange factor, and the effector rabaptin-5. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
RABGEF1
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