4.0
Summary
| Name |  E2F5View Modifications |
| Full Name | Transcription factor E2F5 |
| Synonyms | E2F-5 | |
| Primary ID | Q15329 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | Transcriptional activator that binds to E2F sites, these sites are present in the promoter of many genes whose products are involved in cell proliferation. May mediate growth factor-initiated signal transduction. It is likely involved in the early responses of resting cells to growth factor stimulation. Specifically required for multiciliate cell differentiation |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | CyclinE/CDK2 | up-regulates activity 
phosphorylation
|
E2F5 | 0.659 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | E2F5 | down-regulates quantity by repression 
transcriptional regulation
|
CBX5 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | E2F5 | up-regulates activity
binding
|
CBP/p300 | 0.592 |
| Publications: | 1 | Organism: | Homo Sapiens | |