Relation Results

Summary

Name LLGL1
Full Name Lethal
Synonyms LLGL, DLG4, Hugl-1, Human homolog to the D-lgl gene protein | DLG4, HUGL, HUGL1
Primary ID Q15334
Links - -
Type protein
Relations 6
Function Cortical cytoskeleton protein found in a complex involved in maintaining cell polarity and epithelial integrity. Involved in the regulation of mitotic ...
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Type: Score: Layout: SPV 
0.6510.460.5250.5780.5780.543PRKCILLGL1Scribble_complex_DLG5-LLGL1_variantScribble_complex_DLG4-LLGL1_variantScribble_complex_DLG3-LLGL1_variantScribble_complex_DLG1-LLGL1_variantScribble_complex_DLG2-LLGL1_variant

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▶Modifications Tables

Relations
Regulator
Mechanism
target
score ℹ
+ PRKCIup-regulates activity img/direct-activation.png phosphorylation LLGL1 0.651
Identifier Residue Sequence Organism Cell Line
SIGNOR-263179 Ser659 RVKSLKKsLRQSFRR Canis lupus familiaris
pmid sentence
This finding indicates that both mLgl-2 and mLgl-1 are phosphorylated in vivo in an aPKC lambda activity-dependent manner.
Publications: 1 Organism: Canis Lupus Familiaris
+ LLGL1form complex img/form-complex.png binding Scribble_complex_DLG5-LLGL1_variant 0.46
Identifier Residue Sequence Organism Cell Line
SIGNOR-270899 Homo sapiens
pmid sentence
The Scribble polarity complex or module is one of the three polarity modules that regulate cell polarity in multiple epithelia including blood-tissue barriers. This protein complex is composed of Scribble, Lethal giant larvae (Lgl) and Discs large (Dlg), which are well conserved across species from fruitflies and worms to mammals.
Publications: 1 Organism: Homo Sapiens
+ LLGL1form complex img/form-complex.png binding Scribble_complex_DLG4-LLGL1_variant 0.525
Identifier Residue Sequence Organism Cell Line
SIGNOR-270903 Homo sapiens
pmid sentence
The Scribble polarity complex or module is one of the three polarity modules that regulate cell polarity in multiple epithelia including blood-tissue barriers. This protein complex is composed of Scribble, Lethal giant larvae (Lgl) and Discs large (Dlg), which are well conserved across species from fruitflies and worms to mammals.
Publications: 1 Organism: Homo Sapiens
+ LLGL1form complex img/form-complex.png binding Scribble_complex_DLG3-LLGL1_variant 0.578
Identifier Residue Sequence Organism Cell Line
SIGNOR-270895 Homo sapiens
pmid sentence
The Scribble polarity complex or module is one of the three polarity modules that regulate cell polarity in multiple epithelia including blood-tissue barriers. This protein complex is composed of Scribble, Lethal giant larvae (Lgl) and Discs large (Dlg), which are well conserved across species from fruitflies and worms to mammals.
Publications: 1 Organism: Homo Sapiens
+ LLGL1form complex img/form-complex.png binding Scribble_complex_DLG1-LLGL1_variant 0.578
Identifier Residue Sequence Organism Cell Line
SIGNOR-270911 Homo sapiens
pmid sentence
The Scribble polarity complex or module is one of the three polarity modules that regulate cell polarity in multiple epithelia including blood-tissue barriers. This protein complex is composed of Scribble, Lethal giant larvae (Lgl) and Discs large (Dlg), which are well conserved across species from fruitflies and worms to mammals.
Publications: 1 Organism: Homo Sapiens
+ LLGL1form complex img/form-complex.png binding Scribble_complex_DLG2-LLGL1_variant 0.543
Identifier Residue Sequence Organism Cell Line
SIGNOR-270907 Homo sapiens
pmid sentence
The Scribble polarity complex or module is one of the three polarity modules that regulate cell polarity in multiple epithelia including blood-tissue barriers. This protein complex is composed of Scribble, Lethal giant larvae (Lgl) and Discs large (Dlg), which are well conserved across species from fruitflies and worms to mammals.
Publications: 1 Organism: Homo Sapiens
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