4.0
Summary
| Name |  PUM3
|
| Full Name | Pumilio homolog 3 |
| Synonyms | HBV X-transactivated gene 5 protein, HBV XAg-transactivated protein 5, Minor histocompatibility antigen HA-8, HLA-HA8 | cPERP-C, KIAA0020, PUF-A, XTP5 |
| Primary ID | Q15397 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Inhibits the poly(ADP-ribosyl)ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress (PubMed:21266351). Binds to double-stranded RNA or DNA without sequence specificity (PubMed:25512524). Involved in development of the eye and of primordial germ cells (By similarity). |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | Cap-binding complex | down-regulates quantity by repression 
post transcriptional regulation
|
PUM3 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |