3.0
Summary
| Name |  DLG2View Modifications |
| Full Name | Disks large homolog 2 |
| Synonyms | Channel-associated protein of synapse-110, Chapsyn-110, Postsynaptic density protein PSD-93 | |
| Primary ID | Q15700 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses (By similarity). |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | FYN | up-regulates activity 
phosphorylation
|
DLG2 | 0.375 |
| Publications: | 1 | Organism: | In Vitro | |
| + | DLG2 | form complex 
binding
|
Scribble_complex_DLG2-LLGL2_variant | 0.484 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | DLG2 | form complex
binding
|
Scribble_complex_DLG2-LLGL1_variant | 0.485 |
| Publications: | 1 | Organism: | Homo Sapiens | |