4.0
Summary
| Name |  STXBP2View Modifications |
| Full Name | Syntaxin-binding protein 2 |
| Synonyms | Protein unc-18 homolog 2, Unc18-2, Protein unc-18 homolog B, Unc-18B | UNC18B |
| Primary ID | Q15833 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | CDK5 | down-regulates 
phosphorylation
|
STXBP2 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | STXBP2 | up-regulates activity 
binding
|
STX11 | 0.629 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | STXBP2 | form complex 
binding
|
STX11-VAMP8 SNARE complex | 0.543 |
| Publications: | 1 | Organism: | Homo Sapiens | |