| Name
|
 CACNA1E
|
| Full Name |
Voltage-dependent R-type calcium channel subunit alpha-1E |
| Synonyms |
Brain calcium channel II, BII, Calcium channel, L type, alpha-1 polypeptide, isoform 6, Voltage-gated calcium channel subunit alpha Cav2.3 | CACH6, CACNL1A6 |
| Primary ID |
Q15878 |
| Links |
 -  -  |
| Type |
protein |
| Relations |
2 |
| Function |
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells (PubMed:30343943). They are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. R-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by nickel. They are however insensitive to dihydropyridines (DHP). Calcium channels containing alpha-1E subunit could be involved in the modulation of firing patterns of neurons which is important for information processing. |
3.0
relocalization
