4.0
Summary
| Name |  VPS72
|
| Full Name | Vacuolar protein sorting-associated protein 72 homolog |
| Synonyms | Protein YL-1, Transcription factor-like 1 | TCFL1, YL1 |
| Primary ID | Q15906 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Deposition-and-exchange histone chaperone specific for H2AZ1, specifically chaperones H2AZ1 and deposits it into nucleosomes. As component of the SRCAP complex, mediates the ATP-dependent exchange of histone H2AZ1/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling. |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | VPS72 | form complex 
binding
|
NuA4 complex | 0.669 |
| Publications: | 1 | Organism: | Homo Sapiens | |